METFORMIN HYDROCHLORIDE 250MG (100PCS)

Product Name: メトグルコ錠 (Metgluco Tablets) / メトホルミン塩酸塩 (Metformin Hydrochloride)

Overview

Metogluco Tablets are a prescription medication that contains Metformin Hydrochloride, an oral antihyperglycemic agent used primarily for the management of type 2 diabetes mellitus. This medication helps to control blood sugar levels and is typically used in conjunction with a proper diet and exercise program.

Indications

• Type 2 Diabetes Management: Effective in improving glycemic control in patients with type 2 diabetes.
• Weight Management: May assist in weight loss for obese patients with diabetes.
• Polycystic Ovary Syndrome (PCOS): Sometimes used off-label to help manage symptoms associated with PCOS.

Key Benefits

• Improves Insulin Sensitivity: Enhances the body’s response to insulin, aiding in better glucose uptake and lower blood sugar levels.
• Reduces Glucose Production: Decreases hepatic glucose production, which helps lower blood sugar levels post-meal.
• Weight Neutral: Unlike some other diabetes medications, Metformin is associated with weight neutrality or mild weight loss.
• Metformin is also called a glucose-optimizing drug, meaning it lowers blood sugar to normal (or non-diabetic) levels. If you are treated with metformin alone, you should not experience hypoglycemia. If metformin is taken with other glucose-optimizing drugs (such as thiazolidinediones, starch blockers, or incretins), you should also not experience hypoglycemia. However, if metformin is taken with insulin-releasing drugs or insulin, hypoglycemia may occur because those drugs increase insulin levels, which increases the risk of hypoglycemia. In general, metformin reduces the amount of glucose produced by the liver.

Dosage and Administration

• Dosage: The dosage of Metogluco should be determined by a healthcare provider based on individual patient needs and blood glucose levels.
• Administration: Usually administered orally, with meals to minimize gastrointestinal side effects.
• Typical Initial Dose: Often starts with 500 mg or 850 mg once or twice daily, with gradual increases as needed.

Precautions and Contraindications

1. Kidney Function: Not recommended for patients with severe renal impairment or those at risk of lactic acidosis.
2. Liver Disease: Use with caution in patients with liver diseases.
3. Side Effects: Common side effects may include gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort.
4. Alcohol Consumption: Patients are advised to limit alcohol intake, as it may increase the risk of lactic acidosis.
5. Side effects of metformin include diarrhea, stomach upset, or cramping. It is important to take metformin with food to reduce gastrointestinal side effects. A very rare side effect is lactic acidosis, which is an excess buildup of lactic acid in the blood. It occurs in less than 1 in 100,000 people taking metformin. Lactic acidosis is very dangerous and is often fatal. In general, people who experience this rare side effect should not be taking metformin in the first place (people with kidney disease, heart failure, or alcoholism).

Monitoring

• Regular monitoring of blood glucose levels and renal function is essential while on Metogluco treatment.

Storage

• Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.